Selinexor, Carfilzomib, and Dexamethasone in Treating Patients With Relapsed or Refractory Multiple Myeloma
Summary
Third Opinion Trial Synopsis:
This study is looking at two drugs (selinexor and carfilzomib) and how they work with another drug called dexamethasone to treat a type of cancer called multiple myeloma. These drugs work in different ways to stop cancer cell growth. By using them together, it may be a better way to treat this cancer. The study is looking at the side effects and the best dose for these drugs to use on patients whose cancer has come back or is not responding to previous treatment.
This study is looking at two drugs (selinexor and carfilzomib) and how they work with another drug called dexamethasone to treat a type of cancer called multiple myeloma. These drugs work in different ways to stop cancer cell growth. By using them together, it may be a better way to treat this cancer. The study is looking at the side effects and the best dose for these drugs to use on patients whose cancer has come back or is not responding to previous treatment.
*Third Opinion AI Generated Synopsis
Trial Summary
This phase I trial studies the side effects and best dose of selinexor and carfilzomib when given together with dexamethasone in treating patients with multiple myeloma that has returned or does not respond to treatment. Drugs used in chemotherapy, such as selinexor and dexamethasone, work in different ways to stop the growth of cancer cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Carfilzomib may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. Giving selinexor, carfilzomib, and dexamethasone may be a better treatment for multiple myeloma.
This phase I trial studies the side effects and best dose of selinexor and carfilzomib when given together with dexamethasone in treating patients with multiple myeloma that has returned or does not respond to treatment. Drugs used in chemotherapy, such as selinexor and dexamethasone, work in different ways to stop the growth of cancer cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Carfilzomib may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. Giving selinexor, carfilzomib, and dexamethasone may be a better treatment for multiple myeloma.
Locations & Contact
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