Personalized NK Cell Therapy in CBT
Summary
Third Opinion Trial Synopsis:
This is a study to see if personalized natural killer (NK) cell therapy works well for patients with certain types of cancer after chemotherapy and cord blood transplant. They will be checking if choosing cord blood based on specific markers and using NK cells can kill cancer cells and reduce certain risks.
This is a study to see if personalized natural killer (NK) cell therapy works well for patients with certain types of cancer after chemotherapy and cord blood transplant. They will be checking if choosing cord blood based on specific markers and using NK cells can kill cancer cells and reduce certain risks.
*Third Opinion AI Generated Synopsis
Trial Summary
This phase II clinical trial studies how well personalized natural killer (NK) cell therapy works after chemotherapy and umbilical cord blood transplant in treating patients with myelodysplastic syndrome, leukemia, lymphoma or multiple myeloma. This clinical trial will test cord blood (CB) selection for human leukocyte antigen (HLA)-C1/x recipients based on HLA-killer-cell immunoglobulin-like receptor (KIR) typing, and adoptive therapy with CB-derived NK cells for HLA-C2/C2 patients. Natural killer cells may kill tumor cells that remain in the body after chemotherapy treatment and lessen the risk of graft versus host disease after cord blood transplant.
This phase II clinical trial studies how well personalized natural killer (NK) cell therapy works after chemotherapy and umbilical cord blood transplant in treating patients with myelodysplastic syndrome, leukemia, lymphoma or multiple myeloma. This clinical trial will test cord blood (CB) selection for human leukocyte antigen (HLA)-C1/x recipients based on HLA-killer-cell immunoglobulin-like receptor (KIR) typing, and adoptive therapy with CB-derived NK cells for HLA-C2/C2 patients. Natural killer cells may kill tumor cells that remain in the body after chemotherapy treatment and lessen the risk of graft versus host disease after cord blood transplant.
Locations & Contact
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