CS1-CAR T Therapy Following Chemotherapy in Treating Patients With Relapsed or Refractory CS1 Positive Multiple Myeloma
Summary
Third Opinion Trial Synopsis:
This study is testing a new treatment for people with a type of cancer called multiple myeloma. The treatment involves taking immune cells and changing them so they can recognize and kill cancer cells. It is hoped that this treatment will work for people with multiple myeloma that has come back or is not responding to other treatments.
This study is testing a new treatment for people with a type of cancer called multiple myeloma. The treatment involves taking immune cells and changing them so they can recognize and kill cancer cells. It is hoped that this treatment will work for people with multiple myeloma that has come back or is not responding to other treatments.
*Third Opinion AI Generated Synopsis
Trial Summary
This phase I trial studies the side effects and best dose of CS1-chimeric antigen receptor (CAR) T therapy after chemotherapy in treating patients who have CS1 positive multiple myeloma that has come back (relapsed) or does not respond to treatment (refractory). Immune cells can be engineered to kill multiple myeloma cells by inserting a piece of deoxyribonucleic acid (DNA) into the immune cells using a lentiviral vector such as CS1, that allows them to recognize multiple myeloma cells. These engineered immune cells, CS1-CAR T cells, may kill multiple myeloma cells.
This phase I trial studies the side effects and best dose of CS1-chimeric antigen receptor (CAR) T therapy after chemotherapy in treating patients who have CS1 positive multiple myeloma that has come back (relapsed) or does not respond to treatment (refractory). Immune cells can be engineered to kill multiple myeloma cells by inserting a piece of deoxyribonucleic acid (DNA) into the immune cells using a lentiviral vector such as CS1, that allows them to recognize multiple myeloma cells. These engineered immune cells, CS1-CAR T cells, may kill multiple myeloma cells.
Locations & Contact
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Contacts: