Muscle Stimulation for Physical Function During Stem Cell Transplant
Summary
Third Opinion Trial Synopsis:
Some types of blood cancer are more common in Veterans because of exposure to Agent Orange and being African American. Hematologic transplantation is a common treatment, but it can make people tired and weak. There is currently no treatment to prevent or fix these problems. Exercise before and after treatment can help, but some people don't do it. Researchers are testing a new kind of exercise called neuromuscular electrical stimulation to see if it can help people feel better after treatment.
Some types of blood cancer are more common in Veterans because of exposure to Agent Orange and being African American. Hematologic transplantation is a common treatment, but it can make people tired and weak. There is currently no treatment to prevent or fix these problems. Exercise before and after treatment can help, but some people don't do it. Researchers are testing a new kind of exercise called neuromuscular electrical stimulation to see if it can help people feel better after treatment.
*Third Opinion AI Generated Synopsis
Trial Summary
Some blood, bone marrow, and lymphatic (hematologic) cancers such as Hodgkin/Non-Hodgkin lymphomas, chronic lymphocytic leukemia, and multiple myeloma, are over-represented in Veterans due to exposures including Agent Orange and an increased percentage of patients of African American ethnicity. Hematologic transplantation (HCT) is a common treatment for these cancers, but often leads to deconditioning, fatigue, muscle atrophy, and poor quality of life, which are associated with complications such as hospitalization and infection. Despite the significance of these symptoms, there are no approved treatments to prevent/reverse these long-term effects. The cancer itself, side effects of chemotherapy, and sedentary behavior, contribute to these effects. Although exercise before and after HCT has helped reduce these effects, it is inconsistently recommended to patients and most remain sedentary through and after treatment. The investigators are testing an alternative exercise strategy, neuromuscular electrical stimulation, to maintain physical function quality of life after HCT.
Some blood, bone marrow, and lymphatic (hematologic) cancers such as Hodgkin/Non-Hodgkin lymphomas, chronic lymphocytic leukemia, and multiple myeloma, are over-represented in Veterans due to exposures including Agent Orange and an increased percentage of patients of African American ethnicity. Hematologic transplantation (HCT) is a common treatment for these cancers, but often leads to deconditioning, fatigue, muscle atrophy, and poor quality of life, which are associated with complications such as hospitalization and infection. Despite the significance of these symptoms, there are no approved treatments to prevent/reverse these long-term effects. The cancer itself, side effects of chemotherapy, and sedentary behavior, contribute to these effects. Although exercise before and after HCT has helped reduce these effects, it is inconsistently recommended to patients and most remain sedentary through and after treatment. The investigators are testing an alternative exercise strategy, neuromuscular electrical stimulation, to maintain physical function quality of life after HCT.
Locations & Contact
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