Belantamab Mafodotin and Lenalidomide for the Treatment of Multiple Myeloma in Patients With Minimal Residual Disease Positive After Stem Cell Transplant
Summary
Third Opinion Trial Synopsis:
This study is testing two medicines, belantamab mafodotin and lenalidomide, to see if they can help people with multiple myeloma who still have cancer cells after a stem cell transplant. Belantamab mafodotin targets cancer cells and delivers a chemotherapy drug to kill them. Lenalidomide may stop cancer from growing. Using these two medicines together could help keep the cancer from coming back.
This study is testing two medicines, belantamab mafodotin and lenalidomide, to see if they can help people with multiple myeloma who still have cancer cells after a stem cell transplant. Belantamab mafodotin targets cancer cells and delivers a chemotherapy drug to kill them. Lenalidomide may stop cancer from growing. Using these two medicines together could help keep the cancer from coming back.
*Third Opinion AI Generated Synopsis
Trial Summary
This phase II trial investigates the effect of belantamab mafodotin and lenalidomide on minimal residual disease negative rates in patients with multiple myeloma with minimal residual disease positive after stem cell transplant. Belantamab mafodotin is a monoclonal antibody, called belantamab, linked to a chemotherapy drug, called mafodotin. Belantamab is a form of targeted therapy because it attaches to specific molecules (receptors) on the surface of cancer cells, known as B-cell maturation antigen (BCMA) receptors, and delivers mafodotin to kill them. Lenalidomide may help block the formation of growths that may become cancer, and is used as a standard of care treatment for multiple myeloma. Giving belantamab mafodotin and lenalidomide may help to maintain minimal residual disease negativity in patients with multiple myeloma.
This phase II trial investigates the effect of belantamab mafodotin and lenalidomide on minimal residual disease negative rates in patients with multiple myeloma with minimal residual disease positive after stem cell transplant. Belantamab mafodotin is a monoclonal antibody, called belantamab, linked to a chemotherapy drug, called mafodotin. Belantamab is a form of targeted therapy because it attaches to specific molecules (receptors) on the surface of cancer cells, known as B-cell maturation antigen (BCMA) receptors, and delivers mafodotin to kill them. Lenalidomide may help block the formation of growths that may become cancer, and is used as a standard of care treatment for multiple myeloma. Giving belantamab mafodotin and lenalidomide may help to maintain minimal residual disease negativity in patients with multiple myeloma.
Locations & Contact
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