Venetoclax and Tocilizumab for the Treatment of Patients With Relapsed or Refractory t(11;14) Multiple Myeloma
Summary
Third Opinion Trial Synopsis:
Scientists want to find out the best amount of medicine to give patients with a type of cancer called t(11;14) multiple myeloma, which is hard to treat. They are trying a combination of two types of medicine, venetoclax and tocilizumab, to see if it can kill more cancer cells. Venetoclax stops cancer cells from growing, and tocilizumab interferes with how the cancer cells spread.
Scientists want to find out the best amount of medicine to give patients with a type of cancer called t(11;14) multiple myeloma, which is hard to treat. They are trying a combination of two types of medicine, venetoclax and tocilizumab, to see if it can kill more cancer cells. Venetoclax stops cancer cells from growing, and tocilizumab interferes with how the cancer cells spread.
*Third Opinion AI Generated Synopsis
Trial Summary
This phase I trial finds out the best dose and side effects of venetoclax and tocilizumab in treating patients with t(11;14) multiple myeloma that has come back (relapsed) or does not respond to treatment (refractory). Venetoclax may stop the growth of cancer cells by blocking Bcl-2, a protein needed for cancer cell survival. Tocilizumab is a monoclonal antibody that may interfere with the ability of tumor cells to grow and spread. Tocilizumab is used to treat side effects from immune therapy in patients with myeloma. Giving venetoclax and tocilizumab may kill more cancer cells.
This phase I trial finds out the best dose and side effects of venetoclax and tocilizumab in treating patients with t(11;14) multiple myeloma that has come back (relapsed) or does not respond to treatment (refractory). Venetoclax may stop the growth of cancer cells by blocking Bcl-2, a protein needed for cancer cell survival. Tocilizumab is a monoclonal antibody that may interfere with the ability of tumor cells to grow and spread. Tocilizumab is used to treat side effects from immune therapy in patients with myeloma. Giving venetoclax and tocilizumab may kill more cancer cells.
Locations & Contact
Fill out the form and "Notify Multiple Myeloma Research Foundation" to let the Multiple Myeloma Research Foundation know you are interested in this trial.
Contacts: